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Development of microfluidic devices to control cellular behaviors

Development of microfluidic devices to control cellular behaviors

  • The integrated microfluidic culture device consists of an air control channel and a fluidic channel with 4×4 micropillar arrays.
  • The microscale posts within the micropillar arrays enable the control of uniform cell docking and shear stress profiles. It was demonstrated that the cells were uniformly docked within micropillar arrays and stem cells cultured for 6 days in the integrated microfluidic culture device differentiated into endothelial cells.
Figure 3. Development of the microfluidic device. (A) 4×4 micropillar arrays in the microfluidic device. (B) Uniform cell docking inside micropillar arrays in the microfluidic device.

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